The Fort Wayne Center for Medical Education (FWCME) is located on the Indiana University–Purdue University Fort Wayne campus (IPFW). The center occupies the third floor of the modern Classroom Medical Building.

The center's educational and research facilities include classrooms, teaching and computer laboratories, well-equipped individual faculty research laboratories, and a medical library. IPFW, located along the St. Joseph River in the northeastern section of Fort Wayne, is one of the most spacious and picturesque campuses in the state. The campus has an average enrollment of 10,000 undergraduate and graduate students, making it the fifth largest university in the state. IPFW offers numerous academic programs and allows the center's students access to well-equipped computer facilities, the campus library, the student union, and a sports center equipped with various courts, a track, and a variety of exercise equipment.

Eight tenured full-time faculty are involved in the first- and second-year programs. The faculty includes expert instructors in the fields of medical biochemistry, anatomy, histology, cell biology, embryology, microbiology, immunology, physiology, pharmacology, and neuroscience. Five part-time faculty serve as course directors for Introduction to Clinical Care for freshman, Introduction to Medicine for sophomores, General and Systemic Pathology, Biostatistics, and Medical Genetics.

The Fort Wayne Center's first-year academic program is based on semesters: Gross Anatomy, Biochemistry, and Histology/Embryology are offered in the first semester. The second semester offers Medical Physiology, Neuroscience, and Microbiology/Immunology. For two hours per week throughout the first year, students gain clinical experience in history taking, patient/doctor relationships, etc., in the Introduction to Clinical Care course. The second-year academic program follows a modified semester format, with Medical Pharmacology, Biostatistics, Medical Genetics, and General Pathology being offered in the first semester. Systemic Pathology is offered in the second semester. The Introduction to Medicine course spans both semesters of the sophomore year and includes aspects of advanced history taking, medical ethics, nutrition, physical diagnosis, radiology, infectious diseases, cardiology, etc. More than 160 local physicians have medical school clinical faculty appointments and participate in both the first- and second-year programs.

The Fort Wayne Medical Education Program offers family practice and orthopedic residencies in collaboration with the three community hospitals (Parkview, St. Joseph's, and Lutheran) and the Veterans Administration Medical Center. A variety of junior clerkships and senior electives, as well as continuing medical education events for both students and practicing physicians are offered. Physicians, residents, and hospital personnel are easily accessible to medical students and enthusiastically provide informal clinical training and advice on career planning.

Fort Wayne is one of the 10 cities in 1998 to earn the All-America City title from the National Civic League. With a population of 195,000, it is the second largest metropolitan area in the state. The Botanical Garden, award-winning Fort Wayne Children's Zoo, Art Museum, Philharmonic, Performing Arts Center, and historical attractions provide its residents with cultural activities. Fort Wayne has professional hockey and baseball teams. Eighty-seven parks and playgrounds, covering over 2,000 acres of public park land, and nearby state parks offer recreational activities for outdoor enthusiasts.